JB, RX5 Audio Editor is pretty impressive. If you're familiar with the iZotope interface, you'll find it fairly intuitive. I've found the processing time to be really fast on my system (Win 7 Pro 64bit, i7 3.2 ghz, SSDs, 32GB DDR4).

    The main problem is getting used to 'reading' the spectrogram. For delicate work, like removing an acoustic guitar from a vocal track, you really need to be able to find the guitar and its harmonics, amongst the vocal and its harmonics. ...that takes a lot of practice.

    So... the software is very much limited by its operator.

    There is the RX Plugin Pack : https://www.izotope.com/en/products/audio-repair/rx-plug-in-pack/

    That'll do a fair whack of what you need at a lower price.