It is unlikely. Yamaha preamps have a good reputation for being clean. The same can be said of Midas (designed) preamps, Focusrite, et al.
Are you simply looking for a different interface for the sound of the preamps? or are there other things you want to change?
I use a Behringer XR18 (with Midas designed preamps) as my interface to Logic, and for use in live recordings. About the only "real" limitation, if you can call it that, is that I can only record at 48 kHz - that has not been a problem for me.
You might want to try placing one of Logic's "vintage" EQ plug-ins on your inputs and turn up the "Drive" knobs. Definitely will color the clean sounds coming from the MG10XU