I haven't tried the Fabfilter De-Esser yet, though I've heard it's quite cool.
Another technique I like using particularly on lead vocals is reducing the gain of the esses, plosives and breath blobs in Melodyne while I'm tuning my vocal comp. Everything is right there and I can hear in real time how it sounds before exporting that vocal file to my session. Then if need be and can further automate.
More than one way to skin an ess.